InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NCOA3

Summary

InnateDB Protein

IDBP-695646.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NCOA3

Protein Name

nuclear receptor coactivator 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009850

InnateDB Gene

IDBG-643108 (NCOA3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 135 interaction(s) predicted by orthology.

Predicted by orthology
Total	135 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003713	transcription coactivator activity
GO:0004402	histone acetyltransferase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0016922	ligand-dependent nuclear receptor binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257	nuclear hormone receptor binding
GO:0046983	protein dimerization activity
GO:0047485	protein N-terminus binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007165	signal transduction
GO:0010628	positive regulation of gene expression
GO:0035264	multicellular organism growth
GO:0045618	positive regulation of keratinocyte differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048589	developmental growth
GO:0060068	vagina development
GO:0060713	labyrinthine layer morphogenesis
GO:0060744	mammary gland branching involved in thelarche
GO:2001141	regulation of RNA biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000014 PAS domain
IPR009110 Nuclear receptor coactivator, interlocking
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR013767 PAS fold
IPR014920 Nuclear receptor coactivator, Ncoa-type, interlocking
IPR014935 Steroid receptor coactivator
IPR017426 Nuclear receptor coactivator

PFAM

PF13188
PF13426
PF00010
PF00989
PF08815
PF08832

PRINTS

PIRSF

PIRSF038181

SMART

SM00091
SM00353

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt