InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PREX1

Summary

InnateDB Protein

IDBP-695667.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PREX1

Protein Name

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000040802

InnateDB Gene

IDBG-643121 (PREX1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005515	protein binding
GO:0005543	phospholipid binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0030217	T cell differentiation
GO:0030593	neutrophil chemotaxis
GO:0032321	positive regulation of Rho GTPase activity
GO:0032855	positive regulation of Rac GTPase activity
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction
GO:0043547	positive regulation of GTPase activity
GO:0045785	positive regulation of cell adhesion
GO:0072593	reactive oxygen species metabolic process
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading