InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RECQL5

Summary

InnateDB Protein

IDBP-695719.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RECQL5

Protein Name

RecQ protein-like 5

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015555

InnateDB Gene

IDBG-643175 (RECQL5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000993	RNA polymerase II core binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006260	DNA replication
GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0007067	mitotic nuclear division
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
GO:0051304	chromosome separation

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016591	DNA-directed RNA polymerase II, holoenzyme
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR004589 DNA helicase, ATP-dependent, RecQ type
IPR006935 Helicase/UvrB domain
IPR010716 RecQ helicase-like 5
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF04851
PF06959
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite