InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CD28

Summary

InnateDB Protein

IDBP-695925.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD28

Protein Name

T-cell-specific surface glycoprotein CD28 precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009792

InnateDB Gene

IDBG-643371 (CD28)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0005070	SH3/SH2 adaptor activity
GO:0005515	protein binding

Biological Process

GO:0002863	positive regulation of inflammatory response to antigenic stimulus
GO:0006955	immune response
GO:0009967	positive regulation of signal transduction
GO:0031295	T cell costimulation
GO:0045060	negative thymic T cell selection
GO:0045066	regulatory T cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046641	positive regulation of alpha-beta T cell proliferation
GO:0048304	positive regulation of isotype switching to IgG isotypes
GO:0050852	T cell receptor signaling pathway
GO:0097190	apoptotic signaling pathway