InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GRIN2C

Summary

InnateDB Protein

IDBP-695950.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GRIN2C

Protein Name

glutamate receptor, ionotropic, N-methyl D-aspartate 2C

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015137

InnateDB Gene

IDBG-643388 (GRIN2C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0004970	ionotropic glutamate receptor activity
GO:0004972	N-methyl-D-aspartate selective glutamate receptor activity
GO:0005215	transporter activity
GO:0005216	ion channel activity
GO:0005234	extracellular-glutamate-gated ion channel activity
GO:0005261	cation channel activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0008104	protein localization
GO:0009611	response to wounding
GO:0033058	directional locomotion
GO:0034220	ion transmembrane transport
GO:0035235	ionotropic glutamate receptor signaling pathway
GO:0035249	synaptic transmission, glutamatergic
GO:0042177	negative regulation of protein catabolic process
GO:0042391	regulation of membrane potential
GO:0050885	neuromuscular process controlling balance
GO:0060079	regulation of excitatory postsynaptic membrane potential

Cellular Component

GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0017146	N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054	cell junction
GO:0030425	dendrite
GO:0045202	synapse
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001320 Ionotropic glutamate receptor
IPR001508 NMDA receptor
IPR001638 Extracellular solute-binding protein, family 3
IPR001828 Extracellular ligand-binding receptor
IPR018884 Glutamate [NMDA] receptor, epsilon subunit, C-terminal
IPR019594 Glutamate receptor, L-glutamate/glycine-binding
IPR028082 Periplasmic binding protein-like I

PFAM

PF00060
PF00497
PF01094
PF10565
PF10613

PRINTS

PR00177

PIRSF

SMART

SM00079
SM00062
SM00918

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt