InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CYBASC3

Summary

InnateDB Protein

IDBP-695973.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYBASC3

Protein Name

Cytochrome b ascorbate-dependent protein 3

Synonyms

CYBASC3;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000024228

InnateDB Gene

IDBG-643417 (CYBASC3)

Protein Structure

UniProt Annotation

Function

Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity). {ECO:0000250}.

Subcellular Localization

Late endosome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005768	endosome
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031902	late endosome membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004877 Cytochrome b561, eukaryote
IPR006593 Cytochrome b561/ferric reductase transmembrane

PFAM

PF03188

PRINTS

PIRSF

SMART

SM00665

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A5D9A7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

615893

UniGene

RefSeq

NP_001092619

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC146220 BT030526

GenPept

AAI46221 ABQ12966