Version 5.4
Bos taurus Protein: ACP5
Summary
InnateDB Protein IDBP-696151.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACP5
Protein Name acid phosphatase 5, tartrate resistant
Synonyms TRAP;
Species Bos taurus
Ensembl Protein ENSBTAP00000006339
InnateDB Gene IDBG-643580 (ACP5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003993 acid phosphatase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0016787 hydrolase activity
Biological Process
GO:0016311 dephosphorylation
GO:0032496 response to lipopolysaccharide
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032695 negative regulation of interleukin-12 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032929 negative regulation of superoxide anion generation
GO:0034097 response to cytokine
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045453 bone resorption
GO:0050728 negative regulation of inflammatory response
GO:0050830 defense response to Gram-positive bacterium
GO:0060349 bone morphogenesis
Cellular Component
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR029052 Metallo-dependent phosphatase-like
PFAM PF00149
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3M8V1
UniProt Splice Variant
Entrez Gene 517002
UniGene Bt.5193
RefSeq NP_001243487
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019487 JN635352
GenPept AEO24285

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca