InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.88926

Summary

InnateDB Protein

IDBP-696153.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.88926

Protein Name

phosphatidylinositol 3-kinase catalytic subunit type 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000037130

InnateDB Gene

IDBG-643590 (BT.88926)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0005488	binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016303	1-phosphatidylinositol-3-kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016773	phosphotransferase activity, alcohol group as acceptor

Biological Process

GO:0000910	cytokinesis
GO:0006468	protein phosphorylation
GO:0016310	phosphorylation
GO:0045022	early endosome to late endosome transport
GO:0046854	phosphatidylinositol phosphorylation
GO:0048015	phosphatidylinositol-mediated signaling

Cellular Component

GO:0005770	late endosome
GO:0005942	phosphatidylinositol 3-kinase complex
GO:0016020	membrane
GO:0030496	midbody
GO:0045335	phagocytic vesicle

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
IPR008290 Phosphatidylinositol 3-kinase, Vps34 type
IPR011009 Protein kinase-like domain
IPR016024 Armadillo-type fold

PFAM

PF00168
PF00454
PF00613
PF00792

PRINTS

PR00360

PIRSF

PIRSF000587

SMART

SM00239
SM00146
SM00145
SM00142

TIGRFAMs

Post-translational Modifications

Modification

Cross-References