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InnateDB Protein
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IDBP-696204.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MAF1
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Protein Name
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Repressor of RNA polymerase III transcription MAF1 homolog
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000016239
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InnateDB Gene
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IDBG-643632 (MAF1)
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Protein Structure
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| Function |
Element of the mTORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
7 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0001030
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RNA polymerase III type 1 promoter DNA binding
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GO:0001031
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RNA polymerase III type 2 promoter DNA binding
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GO:0001032
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RNA polymerase III type 3 promoter DNA binding
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| Biological Process |
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GO:0006351
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transcription, DNA-templated
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0016480
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negative regulation of transcription from RNA polymerase III promoter
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR015257
Repressor of RNA polymerase III transcription Maf1
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| PFAM |
PF09174
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| PRINTS |
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| PIRSF |
PIRSF037240
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
A5D9C6
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
512498
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| UniGene |
Bt.1202
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| RefSeq |
XP_005215224
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| HUGO |
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
BT030545
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| GenPept |
ABQ12985
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Version 5.4