Version 5.4
Bos taurus Protein: STX5
Summary
InnateDB Protein IDBP-696276.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STX5
Protein Name Syntaxin-5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000043848
InnateDB Gene IDBG-643697 (STX5)
Protein Structure
UniProt Annotation
Function Mediates endoplasmic reticulum to Golgi transport. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Note=Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Protein Structure and Domains
PDB ID
InterPro IPR000727 Target SNARE coiled-coil domain
IPR006011 Syntaxin, N-terminal domain
IPR010989 t-SNARE
PFAM PF05739
PF00804
PRINTS
PIRSF
SMART SM00397
SM00503
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q08DB5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 510312
UniGene Bt.12416
RefSeq NP_001068912
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123843
GenPept AAI23844

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca