InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CACNG1

Summary

InnateDB Protein

IDBP-696344.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CACNG1

Protein Name

Voltage-dependent calcium channel gamma-1 subunit

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009930

InnateDB Gene

IDBG-643765 (CACNG1)

Protein Structure

UniProt Annotation

Function

This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005244	voltage-gated ion channel activity
GO:0005245	voltage-gated calcium channel activity
GO:0005262	calcium channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006816	calcium ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0070296	sarcoplasmic reticulum calcium ion transport
GO:0070588	calcium ion transmembrane transport

Cellular Component

GO:0005891	voltage-gated calcium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004031 PMP-22/EMP/MP20/Claudin superfamily
IPR005421 Voltage-dependent calcium channel, gamma-1 subunit
IPR008368 Voltage-dependent calcium channel, gamma subunit

PFAM

PF00822
PF13903

PRINTS

PR01601
PR01792

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q08DE1