InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: WHSC1

Summary

InnateDB Protein

IDBP-696522.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WHSC1

Protein Name

Wolf-Hirschhorn syndrome candidate 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010497

InnateDB Gene

IDBG-643914 (WHSC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0008168	methyltransferase activity
GO:0008270	zinc ion binding
GO:0016740	transferase activity
GO:0018024	histone-lysine N-methyltransferase activity
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0003149	membranous septum morphogenesis
GO:0003289	atrial septum primum morphogenesis
GO:0003290	atrial septum secundum morphogenesis
GO:0016568	chromatin modification
GO:0032259	methylation
GO:0034968	histone lysine methylation
GO:0060348	bone development

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000313 PWWP domain
IPR001214 SET domain
IPR001841 Zinc finger, RING-type
IPR001965 Zinc finger, PHD-type
IPR003616 Post-SET domain
IPR006560 AWS domain
IPR009071 High mobility group box domain
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM