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InnateDB Protein
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IDBP-696524.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRMT112
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Protein Name
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tRNA methyltransferase 112 homolog
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Synonyms
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TRM112L; UPF0315;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000011401
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InnateDB Gene
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IDBG-643925 (TRMT112)
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Protein Structure
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| Function |
Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (By similarity). {ECO:0000250}.
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
32 [view]
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| PDB ID |
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| InterPro |
IPR005651
Uncharacterised protein family UPF0434/Trm112
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| PFAM |
PF03966
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q2KIA2
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
507833
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| UniGene |
Bt.55867
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| RefSeq |
NP_001039446
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| HUGO |
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
BC112713
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| GenPept |
AAI12714
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Version 5.4