InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ABCB6

Summary

InnateDB Protein

IDBP-696556.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCB6

Protein Name

ATP-binding cassette sub-family B member 6, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027459

InnateDB Gene

IDBG-643957 (ABCB6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005524	ATP binding
GO:0015439	heme-transporting ATPase activity
GO:0015562	efflux transmembrane transporter activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0020037	heme binding
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0006200	ATP catabolic process
GO:0006779	porphyrin-containing compound biosynthetic process
GO:0006810	transport
GO:0007420	brain development
GO:0015886	heme transport
GO:0043588	skin development
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005740	mitochondrial envelope
GO:0005741	mitochondrial outer membrane
GO:0005768	endosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0031307	integral component of mitochondrial outer membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00664
PF13748
PF00005

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite