Bos taurus Protein: EOMES
Summary
InnateDB Protein IDBP-696662.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EOMES
Protein Name eomesodermin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000053845
InnateDB Gene IDBG-644058 (EOMES)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0001191 RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001706 endoderm formation
GO:0001707 mesoderm formation
GO:0001714 endodermal cell fate specification
GO:0001824 blastocyst development
GO:0001829 trophectodermal cell differentiation
GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007420 brain development
GO:0010002 cardioblast differentiation
GO:0010468 regulation of gene expression
GO:0019827 stem cell maintenance
GO:0021772 olfactory bulb development
GO:0021796 cerebral cortex regionalization
GO:0021895 cerebral cortex neuron differentiation
GO:0030154 cell differentiation
GO:0032609 interferon-gamma production
GO:0035914 skeletal muscle cell differentiation
GO:0045597 positive regulation of cell differentiation
GO:0045664 regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050767 regulation of neurogenesis
GO:0060706 cell differentiation involved in embryonic placenta development
GO:0060809 mesodermal to mesenchymal transition involved in gastrulation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001699 Transcription factor, T-box
IPR008967 p53-like transcription factor, DNA-binding
PFAM PF00907
PRINTS PR00937
PIRSF
SMART SM00425
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MF18
UniProt Splice Variant
Entrez Gene 511947
UniGene Bt.56198
RefSeq NP_001178117
HUGO HGNC:3372
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053460
GenPept