InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NDC80

Summary

InnateDB Protein

IDBP-696772.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDC80

Protein Name

NDC80 homolog, kinetochore complex component (S. cerevisiae)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000031011

InnateDB Gene

IDBG-644146 (NDC80)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 51 interaction(s) predicted by orthology.

Predicted by orthology
Total	51 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0004871	signal transducer activity
GO:0005515	protein binding

Biological Process

GO:0000132	establishment of mitotic spindle orientation
GO:0006355	regulation of transcription, DNA-templated
GO:0007052	mitotic spindle organization
GO:0007059	chromosome segregation
GO:0007165	signal transduction
GO:0008608	attachment of spindle microtubules to kinetochore

Cellular Component

GO:0000776	kinetochore
GO:0000777	condensed chromosome kinetochore
GO:0000942	condensed nuclear chromosome outer kinetochore
GO:0031262	Ndc80 complex

Protein Structure and Domains

PDB ID

InterPro

IPR005550 Kinetochore protein Ndc80
IPR015988 STAT transcription factor, coiled coil

PFAM

PF03801

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02056713

GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca