Version 5.4
Bos taurus Protein: OVOL1
Summary
InnateDB Protein IDBP-696853.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OVOL1
Protein Name Putative transcription factor Ovo-like 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000016791
InnateDB Gene IDBG-644233 (OVOL1)
Protein Structure
UniProt Annotation
Function Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001822 kidney development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007010 cytoskeleton organization
GO:0007283 spermatogenesis
GO:0007498 mesoderm development
GO:0008544 epidermis development
GO:0009913 epidermal cell differentiation
GO:0043588 skin development
GO:0051729 germline cell cycle switching, mitotic to meiotic cell cycle
GO:1901994 negative regulation of meiotic cell cycle phase transition
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2VDT4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 513727
UniGene Bt.24698
RefSeq NP_001074990
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133390
GenPept AAI33391

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca