InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SCN10A

Summary

InnateDB Protein

IDBP-696991.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SCN10A

Protein Name

sodium channel, voltage-gated, type X, alpha subunit

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000054657

InnateDB Gene

IDBG-644347 (SCN10A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005248	voltage-gated sodium channel activity
GO:0005272	sodium channel activity

Biological Process

GO:0002027	regulation of heart rate
GO:0006810	transport
GO:0006811	ion transport
GO:0006814	sodium ion transport
GO:0019228	neuronal action potential
GO:0019233	sensory perception of pain
GO:0034765	regulation of ion transmembrane transport
GO:0035725	sodium ion transmembrane transport
GO:0055085	transmembrane transport
GO:0055117	regulation of cardiac muscle contraction
GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
GO:0061337	cardiac conduction
GO:0086010	membrane depolarization during action potential
GO:0086067	AV node cell to bundle of His cell communication
GO:0086069	bundle of His cell to Purkinje myocyte communication

Cellular Component

GO:0001518	voltage-gated sodium channel complex
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon
GO:0044299	C-fiber
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001696 Voltage gated sodium channel, alpha subunit
IPR005821 Ion transport domain
IPR010526 Sodium ion transport-associated
IPR013122 Polycystin cation channel, PKD1/PKD2

PFAM

PF00520
PF06512
PF08016

PRINTS

PR00170

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite