InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AES

Summary

InnateDB Protein

IDBP-697099.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AES

Protein Name

amino-terminal enhancer of split

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003167

InnateDB Gene

IDBG-644452 (AES)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003714	transcription corepressor activity
GO:0005515	protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001501	skeletal system development
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0010629	negative regulation of gene expression
GO:0031668	cellular response to extracellular stimulus
GO:0032091	negative regulation of protein binding
GO:0040008	regulation of growth
GO:0045892	negative regulation of transcription, DNA-templated
GO:0060761	negative regulation of response to cytokine stimulus
GO:0070555	response to interleukin-1
GO:0090090	negative regulation of canonical Wnt signaling pathway
GO:2000210	positive regulation of anoikis

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR005617 Groucho/TLE, N-terminal Q-rich domain

PFAM

PF03920

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3SYY6

UniProt Splice Variant

Entrez Gene

505375

UniGene

Bt.9945

RefSeq

NP_001121969

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC103327 DAAA02019669

GenPept

AAI03328