InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SKOR2

Summary

InnateDB Protein

IDBP-697287.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SKOR2

Protein Name

SKI family transcriptional corepressor 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000044054

InnateDB Gene

IDBG-644638 (SKOR2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003714	transcription corepressor activity
GO:0042826	histone deacetylase binding
GO:0046332	SMAD binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0021587	cerebellum morphogenesis
GO:0021702	cerebellar Purkinje cell differentiation
GO:0021936	regulation of cerebellar granule cell precursor proliferation
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514	negative regulation of BMP signaling pathway
GO:0045880	positive regulation of smoothened signaling pathway
GO:0048814	regulation of dendrite morphogenesis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR003380 Transforming protein Ski
IPR009061 DNA binding domain, putative
IPR010919 SAND domain-like
IPR014890 c-SKI SMAD4-binding domain

PFAM

PF02437
PF08782

PRINTS

PIRSF

SMART

SM01046

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BCC6

UniProt Splice Variant

Entrez Gene

UniGene

Bt.39234

RefSeq

HUGO

HGNC:32695

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02056929 DAAA02056930 DAAA02056931

GenPept