InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SMAD2

Summary

InnateDB Protein

IDBP-697294.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMAD2

Protein Name

mothers against decapentaplegic homolog 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000036451

InnateDB Gene

IDBG-644642 (SMAD2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 329 interaction(s) predicted by orthology.

Predicted by orthology
Total	329 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005667	transcription factor complex

Protein Structure and Domains

PDB ID

InterPro

IPR001132 SMAD domain, Dwarfin-type
IPR003619 MAD homology 1, Dwarfin-type
IPR008984 SMAD/FHA domain
IPR013019 MAD homology, MH1
IPR019471 Interferon regulatory factor-3

PFAM

PF03166
PF03165
PF10401

PRINTS

PIRSF

SMART

SM00524
SM00523

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite