Bos taurus Protein: IL3
Summary
InnateDB Protein IDBP-697363.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL3
Protein Name Interleukin-3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002774
InnateDB Gene IDBG-644703 (IL3)
Protein Structure
UniProt Annotation
Function Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. {ECO:0000250}.This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005135 interleukin-3 receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0006955 immune response
GO:0008284 positive regulation of cell proliferation
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR002183 Interleukin-3
IPR009079 Four-helical cytokine-like, core
PFAM PF02059
PRINTS PR00430
PIRSF PIRSF001939
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P49875
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280823
UniGene Bt.538
RefSeq NP_776345
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL L31893 U72065
GenPept AAA99502 AAB17188