Version 5.4
Bos taurus Protein: FABP3
Summary
InnateDB Protein IDBP-697408.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FABP3
Protein Name Fatty acid-binding protein, heart
Synonyms FABP; FABP-3; H-FABP;
Species Bos taurus
Ensembl Protein ENSBTAP00000022375
InnateDB Gene IDBG-644743 (FABP3)
Protein Structure
UniProt Annotation
Function FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.MDGI reversibly inhibits proliferation of mammary carcinoma cells.
Subcellular Localization Cytoplasm. Mitochondrion matrix.
Disease Associations
Tissue Specificity Mammary epithelial cells of developing lobuloalveolar structures and heart.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008289 lipid binding
GO:0036041 long-chain fatty acid binding
GO:0070538 oleic acid binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding domain
IPR011038 Calycin-like
PFAM PF00061
PF08212
PRINTS PR00178
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P10790
PhosphoSite PhosphoSite-
TrEMBL Q6VTH7
UniProt Splice Variant
Entrez Gene 281758
UniGene
RefSeq NP_776738
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY327461 BC102153 BT021486 DQ174319 X12710 X51933
GenPept AAI02154 AAQ84682 AAX46333 AAZ99892 CAA31212 CAA36199

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca