InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TRNAU1AP

Summary

InnateDB Protein

IDBP-697546.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRNAU1AP

Protein Name

tRNA selenocysteine 1-associated protein 1

Synonyms

TRSPAP1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000013718

InnateDB Gene

IDBG-644875 (TRNAU1AP)

Protein Structure

UniProt Annotation

Function

Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Abundant in the nucleus. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001514	selenocysteine incorporation
GO:0006412	translation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q1RMJ7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

532582

UniGene

Bt.19750

RefSeq

NP_001069435

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC114858

GenPept

AAI14859