InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SESN2

Summary

InnateDB Protein

IDBP-697570.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SESN2

Protein Name

Sestrin-2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000055856

InnateDB Gene

IDBG-644892 (SESN2)

Protein Structure

UniProt Annotation

Function

Involved in the reduction of peroxiredoxins. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0001932	regulation of protein phosphorylation
GO:0006635	fatty acid beta-oxidation
GO:0006914	autophagy
GO:0007005	mitochondrion organization
GO:0009749	response to glucose
GO:0032042	mitochondrial DNA metabolic process
GO:0032868	response to insulin
GO:0042593	glucose homeostasis
GO:0043491	protein kinase B signaling
GO:0046323	glucose import
GO:0070328	triglyceride homeostasis
GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis
GO:1901031	regulation of response to reactive oxygen species
GO:2000479	regulation of cAMP-dependent protein kinase activity

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR006730 Sestrin
IPR029032 AhpD-like

PFAM

PF04636

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q58CN8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

509863

UniGene

Bt.31388

RefSeq

NP_001019678

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC123386 BT021909

GenPept

AAI23387 AAX46756