Version 5.4
Bos taurus Protein: GAL
Summary
InnateDB Protein IDBP-697593.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAL
Protein Name Galanin peptidesGalaninGalanin message-associated peptide
Synonyms GALN;
Species Bos taurus
Ensembl Protein ENSBTAP00000012362
InnateDB Gene IDBG-644926 (GAL)
Protein Structure
UniProt Annotation
Function Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0005515 protein binding
GO:0031764 type 1 galanin receptor binding
GO:0031765 type 2 galanin receptor binding
GO:0031766 type 3 galanin receptor binding
Biological Process
GO:0007218 neuropeptide signaling pathway
GO:0007399 nervous system development
GO:0010737 protein kinase A signaling
GO:0019933 cAMP-mediated signaling
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051464 positive regulation of cortisol secretion
GO:0051795 positive regulation of catagen
GO:1902608 positive regulation of large conductance calcium-activated potassium channel activity
GO:1902891 negative regulation of root hair elongation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR008174 Galanin
IPR008175 Galanin precursor
IPR013068 Galanin message associated peptide (GMAP)
PFAM PF01296
PF06540
PRINTS PR00273
PIRSF
SMART SM00071
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P11242
PhosphoSite PhosphoSite-
TrEMBL B6JU26
UniProt Splice Variant
Entrez Gene 280799
UniGene
RefSeq NP_776339
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126798 DQ146944 S68957 X12582
GenPept AAD14027 AAI26799 AAZ85123 CAA31094

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca