InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RPA2

Summary

InnateDB Protein

IDBP-697659.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPA2

Protein Name

replication protein A2, 32kDa

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000008174

InnateDB Gene

IDBG-644982 (RPA2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 88 interaction(s) predicted by orthology.

Predicted by orthology
Total	88 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003684	damaged DNA binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0019903	protein phosphatase binding
GO:0031625	ubiquitin protein ligase binding

Biological Process

GO:0000723	telomere maintenance
GO:0000724	double-strand break repair via homologous recombination
GO:0006260	DNA replication
GO:0006281	DNA repair
GO:0006284	base-excision repair
GO:0006289	nucleotide-excision repair
GO:0006298	mismatch repair
GO:0006310	DNA recombination
GO:0010569	regulation of double-strand break repair via homologous recombination
GO:0031571	mitotic G1 DNA damage checkpoint
GO:2000001	regulation of DNA damage checkpoint

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005634	nucleus
GO:0005662	DNA replication factor A complex
GO:0016605	PML body
GO:0035861	site of double-strand break

Protein Structure and Domains

PDB ID

InterPro

IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
IPR012340 Nucleic acid-binding, OB-fold
IPR014646 Replication factor A protein 2
IPR014892 Replication protein A, C-terminal

PFAM

PF01336
PF08784

PRINTS

PIRSF

PIRSF036949

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite