InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ATP6V1C1

Summary

InnateDB Protein

IDBP-697711.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP6V1C1

Protein Name

V-type proton ATPase subunit C 1

Synonyms

vatC;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017968

InnateDB Gene

IDBG-645028 (ATP6V1C1)

Protein Structure

UniProt Annotation

Function

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0015078	hydrogen ion transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0015991	ATP hydrolysis coupled proton transport
GO:0015992	proton transport

Cellular Component

GO:0005765	lysosomal membrane
GO:0005886	plasma membrane
GO:0033180	proton-transporting V-type ATPase, V1 domain
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR004907 ATPase, V1 complex, subunit C

PFAM

PF03223

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P21282

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

338089

UniGene

Bt.52307

RefSeq

NP_788849

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC119957 J05681

GenPept

AAA30803 AAI19958