InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SUCLG2

Summary

InnateDB Protein

IDBP-697755.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SUCLG2

Protein Name

Succinyl-CoA ligase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000012551

InnateDB Gene

IDBG-645076 (SUCLG2)

Protein Structure

UniProt Annotation

Function

Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003824	catalytic activity
GO:0004776	succinate-CoA ligase (GDP-forming) activity
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0016874	ligase activity

Biological Process

GO:0006099	tricarboxylic acid cycle
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR005809 Succinyl-CoA synthetase, beta subunit
IPR005811 ATP-citrate lyase/succinyl-CoA ligase
IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type
IPR016102 Succinyl-CoA synthetase-like

PFAM

PF00549
PF08442

PRINTS

PIRSF

PIRSF001554

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3MHX5