Version 5.4
Homo sapiens Protein: SMC1A
Summary
InnateDB Protein IDBP-69779.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMC1A
Protein Name structural maintenance of chromosomes 1A
Synonyms CDLS2; DXS423E; SB1.8; SMC1; SMC1alpha; SMC1L1; SMCB;
Species Homo sapiens
Ensembl Protein ENSP00000364489
InnateDB Gene IDBG-69775 (SMC1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 133 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 133 [view]
Protein-Protein 129 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0051276 chromosome organization
Cellular Component
GO:0005694 chromosome
Protein Structure and Domains
PDB ID
InterPro IPR000533 Tropomyosin
IPR003395 RecF/RecN/SMC, N-terminal
IPR010935 SMCs flexible hinge
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00261
PF12718
PF02463
PF06470
PRINTS PR00194
PIRSF
SMART SM00968
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0Y7K8
UniProt Splice Variant
Entrez Gene 8243
UniGene Hs.623440
RefSeq NP_001268392
HUGO HGNC:11111
OMIM 300040
CCDS CCDS75985
HPRD 02077
IMGT
EMBL AL161779 Z97054
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca