InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ABHD6

Summary

InnateDB Protein

IDBP-697903.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABHD6

Protein Name

Monoacylglycerol lipase ABHD6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022100

InnateDB Gene

IDBG-645211 (ABHD6)

Protein Structure

UniProt Annotation

Function

Has 2-arachidonoylglycerol hydrolase activity. May be a regulator of endocannabinoid signaling pathways. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016787	hydrolase activity
GO:0047372	acylglycerol lipase activity

Biological Process

GO:0008152	metabolic process
GO:0030336	negative regulation of cell migration
GO:0060292	long term synaptic depression
GO:2000124	regulation of endocannabinoid signaling pathway

Cellular Component

GO:0005739	mitochondrion
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0032281	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000073 Alpha/beta hydrolase fold-1
IPR004142 NDRG
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF00561
PF03096

PRINTS

PR00111

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q1LZ86

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

505283

UniGene

Bt.2858

RefSeq

NP_001068664

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC116144

GenPept

AAI16145