Version 5.4
Bos taurus Protein: CCNE2
Summary
InnateDB Protein IDBP-697922.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCNE2
Protein Name G1/S-specific cyclin-E2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006455
InnateDB Gene IDBG-645230 (CCNE2)
Protein Structure
UniProt Annotation
Function Essential for the control of the cell cycle at the late G1 and early S phase. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901 protein kinase binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 G1/S transition of mitotic cell cycle
GO:0006270 DNA replication initiation
GO:0007049 cell cycle
GO:0051301 cell division
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR004367 Cyclin, C-terminal domain
IPR006671 Cyclin, N-terminal
IPR013763 Cyclin-like
IPR014400 Cyclin A/B/D/E/F
PFAM PF02984
PF00134
PRINTS
PIRSF PIRSF001771
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5E9K7
PhosphoSite PhosphoSite-
TrEMBL G5E570
UniProt Splice Variant
Entrez Gene 538436
UniGene Bt.37175
RefSeq NP_001015665
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT020913 DAAA02039464
GenPept AAX08930

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca