Version 5.4
Bos taurus Protein: PAFAH2
Summary
InnateDB Protein IDBP-697942.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAFAH2
Protein Name Platelet-activating factor acetylhydrolase 2, cytoplasmic
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006727
InnateDB Gene IDBG-645247 (PAFAH2)
Protein Structure
UniProt Annotation
Function Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity Expressed at highest levels in liver and at lower levels in other tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR005065 Platelet-activating factor acetylhydrolase
IPR016715 Platelet-activating factor acetylhydrolase, eucaryote
IPR029058 Alpha/Beta hydrolase fold
PFAM PF03403
PRINTS
PIRSF PIRSF018169
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P79106
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282299
UniGene Bt.85181
RefSeq NP_776995
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105148 BT020849 D87559
GenPept AAI05149 AAX08866 BAA13419

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca