Version 5.4
Bos taurus Protein: GEM
Summary
InnateDB Protein IDBP-697972.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GEM
Protein Name GTP-binding protein GEM
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009992
InnateDB Gene IDBG-645276 (GEM)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007067 mitotic nuclear division
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0051276 chromosome organization
GO:0051310 metaphase plate congression
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0009898 cytoplasmic side of plasma membrane
GO:0016020 membrane
GO:0030496 midbody
GO:0051233 spindle midzone
GO:0072686 mitotic spindle
Protein Structure and Domains
PDB ID
InterPro IPR001806 Small GTPase superfamily
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR013684 Mitochondrial Rho-like
IPR017358 Small GTPase superfamily, GEM/REM/Rad
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00071
PF08477
PRINTS PR00449
PIRSF PIRSF038017
SMART SM00174
SM00175
SM00173
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A4IFA1
UniProt Splice Variant
Entrez Gene 538437
UniGene Bt.75582
RefSeq NP_001263234
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134475 DAAA02039467
GenPept AAI34476

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca