InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MTFMT

Summary

InnateDB Protein

IDBP-698022.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MTFMT

Protein Name

Methionyl-tRNA formyltransferase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028820

InnateDB Gene

IDBG-645316 (MTFMT)

Protein Structure

UniProt Annotation

Function

Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism.

Subcellular Localization

Mitochondrion.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004479	methionyl-tRNA formyltransferase activity
GO:0016740	transferase activity
GO:0016742	hydroxymethyl-, formyl- and related transferase activity

Biological Process

GO:0006412	translation
GO:0006413	translational initiation
GO:0009058	biosynthetic process
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR002376 Formyl transferase, N-terminal
IPR005793 Formyl transferase, C-terminal
IPR005794 Methionyl-tRNA formyltransferase
IPR011034 Formyl transferase, C-terminal-like

PFAM

PF00551
PF02911

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O77480

PhosphoSite