Version 5.4
Bos taurus Protein: ATP6V0D2
Summary
InnateDB Protein IDBP-698120.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP6V0D2
Protein Name V-type proton ATPase subunit d 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000028091
InnateDB Gene IDBG-645414 (ATP6V0D2)
Protein Structure
UniProt Annotation
Function Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015078 hydrogen ion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0015991 ATP hydrolysis coupled proton transport
GO:0015992 proton transport
Cellular Component
GO:0005769 early endosome
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0016471 vacuolar proton-transporting V-type ATPase complex
GO:0033179 proton-transporting V-type ATPase, V0 domain
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002843 ATPase, V0 complex, c/d subunit
IPR016727 ATPase, V0 complex, subunit d
PFAM PF01992
PRINTS
PIRSF PIRSF018497
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KJB6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 511839
UniGene Bt.10174
RefSeq NP_001039566
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105425
GenPept AAI05426

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca