InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SMAD6

Summary

InnateDB Protein

IDBP-698164.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMAD6

Protein Name

SMAD family member 6

Synonyms

Smad6-like;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000824

InnateDB Gene

IDBG-645465 (SMAD6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.

Predicted by orthology
Total	38 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
GO:0031625	ubiquitin protein ligase binding
GO:0034713	type I transforming growth factor beta receptor binding
GO:0044212	transcription regulatory region DNA binding
GO:0070410	co-SMAD binding
GO:0070411	I-SMAD binding
GO:0070412	R-SMAD binding
GO:0070698	type I activin receptor binding

Biological Process

GO:0001657	ureteric bud development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006955	immune response
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007352	zygotic specification of dorsal/ventral axis
GO:0008285	negative regulation of cell proliferation
GO:0010991	negative regulation of SMAD protein complex assembly
GO:0030509	BMP signaling pathway
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514	negative regulation of BMP signaling pathway
GO:0031589	cell-substrate adhesion
GO:0034616	response to laminar fluid shear stress
GO:0035556	intracellular signal transduction
GO:0043066	negative regulation of apoptotic process
GO:0045444	fat cell differentiation
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation