InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CHID1

Summary

InnateDB Protein

IDBP-698186.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHID1

Protein Name

Chitinase domain-containing protein 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000013065

InnateDB Gene

IDBG-645355 (CHID1)

Protein Structure

UniProt Annotation

Function

Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro) (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted. Lysosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004568	chitinase activity

Biological Process

GO:0002376	immune system process
GO:0005975	carbohydrate metabolic process
GO:0006032	chitin catabolic process
GO:0045087	innate immune response

Cellular Component

GO:0005576	extracellular region
GO:0005764	lysosome

Protein Structure and Domains

PDB ID

InterPro

IPR001223 Glycoside hydrolase, family 18, catalytic domain
IPR011583 Chitinase II
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF00704

PRINTS

PIRSF

SMART

SM00636

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC118449 BT020630 BT020655 BT020789 BT020873 BT021168 BT021170 BT021178

GenPept

AAI18450 AAX08647 AAX08672 AAX08806 AAX08890 AAX31350 AAX31352 AAX31360

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca