InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EPHB2

Summary

InnateDB Protein

IDBP-698200.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EPHB2

Protein Name

EPH receptor B2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026780

InnateDB Gene

IDBG-645496 (EPHB2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004872	receptor activity
GO:0005003	ephrin receptor activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008046	axon guidance receptor activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000902	cell morphogenesis
GO:0006468	protein phosphorylation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411	axon guidance
GO:0007612	learning
GO:0009887	organ morphogenesis
GO:0016310	phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0021631	optic nerve morphogenesis
GO:0021952	central nervous system projection neuron axonogenesis
GO:0031290	retinal ganglion cell axon guidance
GO:0048013	ephrin receptor signaling pathway
GO:0048168	regulation of neuronal synaptic plasticity
GO:0048170	positive regulation of long-term neuronal synaptic plasticity
GO:0048593	camera-type eye morphogenesis
GO:0050770	regulation of axonogenesis
GO:0050771	negative regulation of axonogenesis

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001660 Sterile alpha motif domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003961 Fibronectin, type III
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR011009 Protein kinase-like domain
IPR011510 Sterile alpha motif, type 2
IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like
IPR013761 Sterile alpha motif/pointed domain
IPR020635 Tyrosine-protein kinase, catalytic domain
IPR021129 Sterile alpha motif, type 1

PFAM