Version 5.4
Bos taurus Protein: WNT4
Summary
InnateDB Protein IDBP-698236.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WNT4
Protein Name wingless-type MMTV integration site family, member 4
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000030714
InnateDB Gene IDBG-645527 (WNT4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005102 receptor binding
GO:0005109 frizzled binding
GO:0005515 protein binding
Biological Process
GO:0001656 metanephros development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001822 kidney development
GO:0001823 mesonephros development
GO:0001837 epithelial to mesenchymal transition
GO:0001838 embryonic epithelial tube formation
GO:0001889 liver development
GO:0006702 androgen biosynthetic process
GO:0007275 multicellular organismal development
GO:0007276 gamete generation
GO:0007548 sex differentiation
GO:0008584 male gonad development
GO:0008585 female gonad development
GO:0009267 cellular response to starvation
GO:0010629 negative regulation of gene expression
GO:0010894 negative regulation of steroid biosynthetic process
GO:0016055 Wnt signaling pathway
GO:0018345 protein palmitoylation
GO:0022407 regulation of cell-cell adhesion
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030237 female sex determination
GO:0030325 adrenal gland development
GO:0030336 negative regulation of cell migration
GO:0030501 positive regulation of bone mineralization
GO:0032321 positive regulation of Rho GTPase activity
GO:0032349 positive regulation of aldosterone biosynthetic process
GO:0032967 positive regulation of collagen biosynthetic process
GO:0033077 T cell differentiation in thymus
GO:0033080 immature T cell proliferation in thymus
GO:0035239 tube morphogenesis
GO:0035567 non-canonical Wnt signaling pathway
GO:0038030 non-canonical Wnt receptor signaling pathway via MAPK cascade
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042445 hormone metabolic process
GO:0045165 cell fate commitment
GO:0045596 negative regulation of cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045836 positive regulation of meiosis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048599 oocyte development
GO:0048754 branching morphogenesis of an epithelial tube
GO:0048856 anatomical structure development
GO:0051145 smooth muscle cell differentiation
GO:0051496 positive regulation of stress fiber assembly
GO:0051894 positive regulation of focal adhesion assembly
GO:0060070 canonical Wnt signaling pathway
GO:0060126 somatotropin secreting cell differentiation
GO:0060129 thyroid-stimulating hormone-secreting cell differentiation
GO:0060231 mesenchymal to epithelial transition
GO:0060748 tertiary branching involved in mammary gland duct morphogenesis
GO:0060993 kidney morphogenesis
GO:0061045 negative regulation of wound healing
GO:0061180 mammary gland epithelium development
GO:0061184 positive regulation of dermatome development
GO:0061205 paramesonephric duct development
GO:0061369 negative regulation of testicular blood vessel morphogenesis
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0072033 renal vesicle formation
GO:0072034 renal vesicle induction
GO:0072164 mesonephric tubule development
GO:0072174 metanephric tubule formation
GO:0072210 metanephric nephron development
GO:0072273 metanephric nephron morphogenesis
GO:0090002 establishment of protein localization to plasma membrane
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:2000019 negative regulation of male gonad development
GO:2000066 positive regulation of cortisol biosynthetic process
GO:2000225 negative regulation of testosterone biosynthetic process
GO:2001234 negative regulation of apoptotic signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0009986 cell surface
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR005817 Wnt
IPR009142 Wnt-4 protein
PFAM PF00110
PRINTS PR01349
PR01844
PIRSF
SMART SM00097
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MZV4
UniProt Splice Variant
Entrez Gene 789600
UniGene
RefSeq XP_003581950
HUGO HGNC:12783
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02006467
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca