Version 5.4
Bos taurus Protein: MED16
Summary
InnateDB Protein IDBP-698263.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED16
Protein Name mediator complex subunit 16
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000055629
InnateDB Gene IDBG-645542 (MED16)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.
Predicted by orthology
Total 64 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003712 transcription cofactor activity
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0030375 thyroid hormone receptor coactivator activity
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0030518 intracellular steroid hormone receptor signaling pathway
GO:0030521 androgen receptor signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:2000273 positive regulation of receptor activity
Cellular Component
GO:0016020 membrane
GO:0016592 mediator complex
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR021665 Mediator complex, subunit Med16
PFAM PF00400
PF11635
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5E6J3
UniProt Splice Variant
Entrez Gene
UniGene Bt.96804
RefSeq
HUGO HGNC:17556
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020234 DAAA02020235
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca