Homo sapiens Protein: CYGB
Summary
InnateDB Protein IDBP-69827.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYGB
Protein Name cytoglobin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000293230
InnateDB Gene IDBG-69825 (CYGB)
Protein Structure
UniProt Annotation
Function May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. {ECO:0000269PubMed:11893755}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004601 peroxidase activity
GO:0005344 oxygen transporter activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
Biological Process
GO:0006979 response to oxidative stress
GO:0015671 oxygen transport
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0043005 neuron projection
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR000971 Globin
IPR002335 Myoglobin
IPR009050 Globin-like
IPR013314 Globin, lamprey/hagfish type
PFAM PF00042
PRINTS PR00613
PR01906
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WWM9
PhosphoSite PhosphoSite-Q8WWM9
TrEMBL K7EIM9
UniProt Splice Variant
Entrez Gene 114757
UniGene Hs.95120
RefSeq NP_599030
HUGO HGNC:16505
OMIM 608759
CCDS CCDS11746
HPRD 06479
IMGT
EMBL AB057769 AC015802 AJ315162 AK098057 BC029798 CH471099
GenPept AAH29798 BAB87840 BAC05223 CAC86186 EAW89406