InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ABCA7

Summary

InnateDB Protein

IDBP-698304.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCA7

Protein Name

ATP-binding cassette, sub-family A (ABC1), member 7

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020083

InnateDB Gene

IDBG-645574 (ABCA7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005524	ATP binding
GO:0005548	phospholipid transporter activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0034188	apolipoprotein A-I receptor activity

Biological Process

GO:0006200	ATP catabolic process
GO:0008152	metabolic process
GO:0017121	phospholipid scrambling
GO:0032780	negative regulation of ATPase activity
GO:0032781	positive regulation of ATPase activity
GO:0033344	cholesterol efflux
GO:0033700	phospholipid efflux
GO:0034380	high-density lipoprotein particle assembly
GO:0038027	apolipoprotein A-I-mediated signaling pathway

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016324	apical plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00005

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BCG1

UniProt Splice Variant

Entrez Gene

511762

UniGene

RefSeq

NP_001192634

HUGO

HGNC:37

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02020246

GenPept