InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: APC2

Summary

InnateDB Protein

IDBP-698361.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APC2

Protein Name

adenomatosis polyposis coli 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000035274

InnateDB Gene

IDBG-645640 (APC2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0008017	microtubule binding

Biological Process

GO:0016055	Wnt signaling pathway
GO:0030178	negative regulation of Wnt signaling pathway
GO:0035414	negative regulation of catenin import into nucleus
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005881	cytoplasmic microtubule
GO:0005884	actin filament
GO:0015630	microtubule cytoskeleton
GO:0016342	catenin complex
GO:0031258	lamellipodium membrane
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000225 Armadillo
IPR009053 Prefoldin
IPR009223 Adenomatous polyposis coli protein, cysteine-rich repeat
IPR009224 SAMP
IPR009234 Adenomatous polyposis coli protein basic domain
IPR016024 Armadillo-type fold
IPR026831 Adenomatous polyposis coli domain

PFAM

PF00514
PF05923
PF05924
PF05956
PF11414

PRINTS

PIRSF

SMART

SM00185

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite