Version 5.4
| Bos taurus Protein: LTB4R | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-698423.2 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | LTB4R | ||||||||||
| Protein Name | Leukotriene B4 receptor 1 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Protein | ENSBTAP00000036335 | ||||||||||
| InnateDB Gene | IDBG-645690 (LTB4R) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response (By similarity). {ECO:0000250}. | ||||||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | |||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR003981 Leukotriene B4 receptor IPR003983 Leukotriene B4 type 1 receptor IPR017452 GPCR, rhodopsin-like, 7TM IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx IPR019430 7TM GPCR, serpentine receptor class x (Srx) |
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| PFAM |
PF00001
PF10320 PF10328 |
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| PRINTS |
PR00237
PR01476 PR01477 |
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| PIRSF | |||||||||||
| SMART | |||||||||||
| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q3T181 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 613482 | ||||||||||
| UniGene | Bt.16889 | ||||||||||
| RefSeq | NP_001029910 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BC102075 | ||||||||||
| GenPept | AAI02076 | ||||||||||