Version 5.4
Bos taurus Protein: UQCRQ
Summary
InnateDB Protein IDBP-698452.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UQCRQ
Protein Name Cytochrome b-c1 complex subunit 8
Synonyms QP-C;
Species Bos taurus
Ensembl Protein ENSBTAP00000040860
InnateDB Gene IDBG-645715 (UQCRQ)
Protein Structure
UniProt Annotation
Function This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
Subcellular Localization Mitochondrion inner membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008121 ubiquinol-cytochrome-c reductase activity
Biological Process
GO:0021539 subthalamus development
GO:0021548 pons development
GO:0021680 cerebellar Purkinje cell layer development
GO:0021766 hippocampus development
GO:0021794 thalamus development
GO:0021854 hypothalamus development
GO:0021860 pyramidal neuron development
GO:0030901 midbrain development
GO:0055114 oxidation-reduction process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0070469 respiratory chain
Protein Structure and Domains
PDB ID
InterPro IPR004205 Cytochrome b-c1 complex subunit 8
PFAM PF02939
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P13271
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 286885
UniGene
RefSeq NP_777230
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103110 L06665
GenPept AAB03845 AAI03111

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca