Version 5.4
Bos taurus Protein: THTPA
Summary
InnateDB Protein IDBP-698523.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THTPA
Protein Name Thiamine-triphosphatase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009334
InnateDB Gene IDBG-645777 (THTPA)
Protein Structure
UniProt Annotation
Function Hydrolase highly specific for thiamine triphosphate (ThTP). {ECO:0000269PubMed:11827967}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:11827967}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050333 thiamin-triphosphatase activity
Biological Process
GO:0006772 thiamine metabolic process
GO:0016311 dephosphorylation
GO:0042357 thiamine diphosphate metabolic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR012177 Thiamine triphosphatase
IPR023577 CYTH-like domain
PFAM PF01928
PRINTS
PIRSF PIRSF036561
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8MKF1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282090
UniGene Bt.8966
RefSeq NP_776895
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF432863 BC105468
GenPept AAI05469 AAM22404

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca