Version 5.4
Bos taurus Protein: NECAP2
Summary
InnateDB Protein IDBP-698598.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NECAP2
Protein Name Adaptin ear-binding coat-associated protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000017663
InnateDB Gene IDBG-645844 (NECAP2)
Protein Structure
UniProt Annotation
Function Involved in endocytosis. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with AP-2 at the plasma membrane. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0006897 endocytosis
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030125 clathrin vesicle coat
GO:0030665 clathrin-coated vesicle membrane
GO:0031410 cytoplasmic vesicle
Protein Structure and Domains
PDB ID
InterPro IPR012466 Adaptin ear-binding coat-associated protein 1 NECAP-1
PFAM PF07933
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5E9Q4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 509439
UniGene Bt.43781
RefSeq NP_001015562
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109915 BT020866
GenPept AAI09916 AAX08883

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca