Version 5.4
Bos taurus Protein: KIF20A
Summary
InnateDB Protein IDBP-698688.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF20A
Protein Name Kinesin-like protein KIF20A
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000011539
InnateDB Gene IDBG-645920 (KIF20A)
Protein Structure
UniProt Annotation
Function Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Subcellular Localization Golgi apparatus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0019901 protein kinase binding
Biological Process
GO:0000910 cytokinesis
GO:0001578 microtubule bundle formation
GO:0006810 transport
GO:0007018 microtubule-based movement
GO:0007165 signal transduction
GO:0008152 metabolic process
GO:0015031 protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005871 kinesin complex
GO:0005874 microtubule
Protein Structure and Domains
PDB ID
InterPro IPR001752 Kinesin, motor domain
IPR011072 HR1 rho-binding repeat
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00225
PF02185
PRINTS PR00380
PIRSF
SMART SM00129
SM00742
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q29RT6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 527854
UniGene Bt.18081
RefSeq NP_001039753
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114026
GenPept AAI14027

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca