Version 5.4
| Bos taurus Protein: ETF1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-698756.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | ETF1 | ||||||||
| Protein Name | Eukaryotic peptide chain release factor subunit 1 | ||||||||
| Synonyms | RRF1; | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000035133 | ||||||||
| InnateDB Gene | IDBG-645989 (ETF1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR004403
Peptide chain release factor eRF1/aRF1 IPR005140 eRF1 domain 1/Pelota-like IPR005141 eRF1 domain 2 IPR005142 eRF1 domain 3 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal IPR029064 50S ribosomal protein L30e-like |
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| PFAM |
PF03463
PF03464 PF03465 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q0VCX5 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 541077 | ||||||||
| UniGene | Bt.27192 | ||||||||
| RefSeq | NP_001069722 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC119947 | ||||||||
| GenPept | AAI19948 | ||||||||